Conray-30 Side Effects
Generic name: iothalamate
Medically reviewed by Drugs.com. Last updated on Aug 5, 2023.
Note: This document contains side effect information about iothalamate. Some dosage forms listed on this page may not apply to the brand name Conray-30.
Applies to iothalamate: injection solution.
Warning
Injection route (Solution)
Not for intrathecal use
Serious side effects of Conray-30
Along with its needed effects, iothalamate (the active ingredient contained in Conray-30) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking iothalamate:
More common
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- bluish color of fingernails, lips, skin, palms, or nail beds
- chest pain or tightness
- cough
- coughing that sometimes produces a pink frothy sputum
- feeling of warmth
- increased sweating
- noisy breathing
- not breathing
- pale skin
- redness of the face, neck, arms and occasionally, upper chest
- swelling in the legs and ankles
- trouble breathing
Rare
- Changes in skin color, pain, tenderness, or swelling of the foot or leg
- chest discomfort
- dizziness
- fainting
- fast, slow, or irregular heartbeat
- lightheadedness
- pounding or rapid pulse
- stopping of the heart
- unconsciousness
Incidence not known
- Black, tarry stools
- blistering, peeling, or loosening of the skin
- blue-green to black skin discoloration
- bruising
- burning, crawling, itching, numbness, prickling, "pins and needles" , or tingling feelings
- chills
- collection of blood under the skin
- constipation
- deep, dark purple bruise
- depressed mood
- diarrhea
- dry mouth
- dry skin and hair
- feeling cold
- hair loss
- hoarseness or husky voice
- itching
- joint or muscle pain
- large, flat, blue or purplish patches in the skin
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- muscle cramps and stiffness
- nervousness
- painful or difficult urination
- partial or slight paralysis
- problems with speech or speaking
- red irritated eyes
- red skin lesions, often with a purple center
- seizures
- sensitivity to heat
- sneezing
- sore throat
- sores, ulcers, or white spots in the mouth or on the lips
- sweating
- swollen glands
- trouble sleeping
- unusual bleeding or bruising
- unusual tiredness or weakness
- weight gain
- weight loss
For Healthcare Professionals
Applies to iothalamate: injectable solution.
Dermatologic
Common (1% to 10%): Pruritus, urticarial, face edema
Uncommon (0.1% to 1%): Erythema, rash
Rare (less than 0.1%): Angioedema, diaphoresis
Frequency not reported: Ecchymosis and tissue necrosis[Ref]
Gastrointestinal
Common (1% to 10%): Nausea, vomiting
Rare (0.01% to 0.1%): Diarrhea, dry mouth, tongue edema
Very rare (less than 0.01%): Dysphagia[Ref]
Hypersensitivity
Rarely, these allergic-type reactions can progress into anaphylaxis with loss of consciousness and coma and severe cardiovascular disturbances.[Ref]
Common (1% to 10%): Anaphylactoid reactions
Frequency not reported: Dermal manifestations (urticaria with or without pruritus, erythema, maculopapular rash); dry mouth, sweating, conjunctival symptoms; facial, peripheral, and angioneurotic edema; symptoms related to the respiratory system include sneezing, nasal stuffiness, coughing, choking, dyspnea, chest tightness and wheezing, which may be initial manifestations of more severe and infrequent reactions including asthmatic attack, laryngospasm and bronchospasm with or without edema, pulmonary edema, apnea and cyanosis[Ref]
Respiratory
Common (1% to 10%): Rhinitis
Uncommon (0.1% to 1%): Coughing, dyspnea
Rare (0.01% to 0.1%): Larynx edema
Very rare (less than 0.01%): Apnea, bronchospasm[Ref]
Cardiovascular
These severe reactions are usually reversible with prompt and appropriate management; however, fatalities have occurred.[Ref]
Uncommon (0.1% to 1%): Hypotension
Rare (0.01% to 0.1%): Thrombophlebitis, tachycardia, ventricular fibrillation, pallor, vasodilation, cyanosis
Very rare (less than 0.01%): Disseminated intravascular coagulation resulting in death; arrhythmia; bradycardia; cardiac arrest, circulatory failure; abnormal ECG; heart block; phlebitis
Frequency not reported: Generalized vasodilation, flushing and venospasm; occasionally thrombosis; severe cardiovascular responses include rare cases of hypotensive shock, coronary insufficiency, cardiac arrhythmia, fibrillation and arrest; extravasation with burning pain; hematomas; vascular constriction due to injection rate; thrombosis[Ref]
Endocrine
Uncommon (0.1% to 1%): Thyroid function tests indicative of hypothyroidism or transient thyroid suppression in adults and pediatric patients (including infants)[Ref]
Ocular
Uncommon (0.1% to 1%): Periorbital edema
Rare (0.01% to 0.1%): Conjunctivitis
Very rare (less than 0.01%): Vision disorders[Ref]
Local
Rare (less than 0.1%): Injection side reaction[Ref]
Nervous system
Rare (0.01% to 0.1%): Dizziness; paraesthesia; taste perversion
Very rare (less than 0.01%): Agitation, coma, convulsions, dyskinesia, paralysis, tremor, somnolence
Frequency not reported: Aphasia; syncope, paresis; paralysis resulting from spinal cord injury and pathology associated with syndrome of transverse myelitis; visual field losses which are usually transient but may be permanent; coma and death; headache, trembling, shaking, numbness[Ref]
Genitourinary
Very rare (less than 0.01%): Urinary incontinence[Ref]
Metabolic
Very rare (less than 0.01%): Thirst[Ref]
Musculoskeletal
Very rare (less than 0.01%): Involuntary muscle contractions, myalgia, leg pain
Frequency not reported: Spasm[Ref]
Other
Very common (10% or more): Hot flushes, pain
Rare (0.01% to 0.1%): Malaise
Very rare (less than 0.01%): Edema, abnormal crying
Frequency not reported: Chills without fever and lightheadedness[Ref]
Psychiatric
Very rare (less than 0.01%): Anxiety[Ref]
Renal
Very rare (less than 0.01%): Acute renal failure, decrease in renal function
Frequency not reported: Temporary renal shutdown or other nephropathy[Ref]
Hematologic
Frequency not reported: Red blood cell clumping and agglutination, crenation and interference in clot formation[Ref]
More about Conray-30 (iothalamate)
- Check interactions
- Compare alternatives
- Latest FDA alerts (2)
- Dosage information
- During pregnancy
- Drug class: ionic iodinated contrast media
- Breastfeeding
Patient resources
Other formulations
References
1. Cerner Multum, Inc. "UK Summary of Product Characteristics."
2. Cerner Multum, Inc. "Australian Product Information."
3. (2015) "Product Information. Conray (iothalamate)." Mallinckrodt Medical Inc
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.