Variation ID'd in Risk for Second Primary Cancer After Breast Cancer
By Elana Gotkine HealthDay Reporter
TUESDAY, April 30, 2024 -- The risk for second primary cancer (SPC) after breast cancer (BC) varies with gender, age, and socioeconomic status, according to a study published online April 24 in The Lancet Regional Health: Europe.
Isaac Allen, from the National Health Service England in London, and colleagues estimated standardized incidence ratios (SIRs) for combined and site-specific SPCs using incidences for England, overall, and by age at BC and socioeconomic status in a cohort including 581,403 female and 3,562 male BC survivors diagnosed between 1995 and 2019.
The researchers found that both women and men had an increased risk for contralateral breast (SIRs, 2.02 for women and 55.4 for men) and nonbreast SPC (SIRs, 1.10 for women and 1.10 for men). Women who were younger at BC diagnosis had higher nonbreast SPC risks (SIRs, 1.34 at younger than 50 years and 1.07 at 50 years or older), as did those who were more socioeconomically deprived (SIR, 1.34 for most deprived quintile).
"We assessed the variation in SPC risks by a wide range of sociodemographic factors, first tumor characteristics, and BC treatments and found that SPC risks are elevated among BC survivors living in more socioeconomically deprived regions at diagnosis," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted April 2024
Read this next
American Society of Clinical Oncology, May 30-June 4
The annual meeting of the American Society of Clinical Oncology was held from May 30 to June 4 in Chicago and hosted more than 34,000 participants from around the world, including...
New Clinical Score Can Predict Immune Checkpoint Blockade Response
MONDAY, June 10, 2024 -- For patients with cancer, a novel clinical score using a six-feature regression model can predict immune checkpoint blockade (ICB) response probability...
Resistance Exercise Boosts Outcomes After Early-Stage Breast Cancer Surgery
FRIDAY, June 7, 2024 -- Early resistance exercise following surgery for early-stage breast cancer improves shoulder range of motion (ROM) and strength at one month and six months...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.