Endolymphatic Hydrops Asymmetry Can Distinguish Meniere Patients From Controls
By Elana Gotkine HealthDay Reporter
MONDAY, Feb. 5, 2024 -- Endolymphatic hydrops (EH) asymmetry can differentiate patients with Meniere disease (MD) from normal controls, according to a study published online Dec. 21 in Frontiers in Neurology.
Tae-Soo Noh, from the Seoul National University College of Medicine in South Korea, and colleagues examined the extent of hydrops in MD patients and age- and sex-matched normal controls to assess which outcome measure most effectively distinguishes between MD patients and controls. Magnetic resonance imaging (MRI) was performed using a 3-T MR platform; MR images covering an inner ear were 3D-stacked. The volumes of the endolymphatic and perilymphatic spaces were yielded on analyses of all images, including the vestibule or cochlea; the quantitative volumetric EH percentage was calculated as the endolymph volume (μL)/(endolymph+perilymph volume [μL]).
The researchers found that the EH percentage was significantly greater in ipsilateral versus contralateral MD ears and in ipsilateral MD ears versus control ears for the vestibule. The values for the cochlea showed a slightly higher EH percentage in ipsilateral MD ears, but did not significantly differ from that seen in contralateral or control ears. The EH asymmetries (right ear minus left ear EH percentage) were 12.0 ± 10.2 and 8.4 ± 8.6 percent in the vestibule and cochlea, respectively, in the MD group, which were significantly larger than those of controls.
"EH asymmetry effectively differentiates MD patients from normal controls," the authors write. "In our study, the sensitivity, specificity, and area under the curve of EH asymmetry were better than those of conventional EH percentage."
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted February 2024
Read this next
Mortality in Rheumatic Heart Disease Is High
FRIDAY, June 7, 2024 -- Mortality related to rheumatic heart disease (RHD) is high and is correlated with the severity of valve disease, according to a study published online June...
Higher County-Level Prostate Cancer Screening Tied to Better Outcomes
FRIDAY, June 7, 2024 -- Higher county-level prevalence of prostate-specific antigen (PSA) screening is associated with lower odds of advanced disease, all-cause mortality, and...
Metabolic Impact on Offspring Similar for Frozen, Fresh Embryo Transfer
FRIDAY, June 7, 2024 -- For glucose and lipid profiles during early childhood, the impact of frozen embryo transfer (FET) is comparable to that of fresh embryo transfer, according...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.