ASA: Women More Likely Than Men to Develop Depression After TBI
Medically reviewed by Drugs.com.
By Elana Gotkine HealthDay Reporter
FRIDAY, Oct. 27, 2023 -- Following traumatic brain injury (TBI), women are significantly more likely to develop depression than men, according to research presented at ANESTHESIOLOGY 2023, the annual meeting of the American Society of Anesthesiologists, held from Oct. 13 to 17 in San Francisco.
Isaac G. Freedman, M.D., M.P.H., from Massachusetts General Hospital in Boston, and colleagues conducted a meta-analysis to examine how gender impacts depression following TBI. Data were included from nine studies, with 691,364 individuals.
The researchers found that women had significantly greater odds of developing depression following TBI than men (odds ratio, 1.48) in the combined analysis of all nine studies and the subset of five studies. Across trials, the odds ratios were significantly heterogeneous (I2 = 92.17 percent). In five studies without significant heterogeneity, the association persisted (odds ratio, 1.48).
"The resulting difference in brain circuits between men and women in combination with factors such as lack of social support, socioeconomic status, and inadequate treatment options may make some women more vulnerable to post-TBI depression," senior author Benjamin F. Gruenbaum, M.D., Ph.D., from the Mayo Clinic in Jacksonville, Florida, said in a statement.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2024 HealthDay. All rights reserved.
Posted October 2023
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