Trulance Alternatives Compared
Trulance | Motegrity | Linzess |
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Trulance (plecanatide) | Motegrity (prucalopride) | Linzess (linaclotide) |
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Prescription only
Prescribed for Chronic Idiopathic Constipation, Irritable Bowel Syndrome with Constipation. Trulance may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Chronic Idiopathic Constipation. Motegrity may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Irritable Bowel Syndrome with Constipation, Chronic Idiopathic Constipation, Functional Constipation, Irritable Bowel Syndrome. Linzess may also be used for purposes not listed in this... View more |
Related suggestions Chronic Idiopathic Constipation
Popular comparisons
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More about Trulance (plecanatide) | More about Motegrity (prucalopride) | More about Linzess (linaclotide) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Trulance has an average rating of 6.0 out of 10 from a total of 273 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 34% reported a negative effect. |
Motegrity has an average rating of 5.9 out of 10 from a total of 66 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 36% reported a negative effect. |
Linzess has an average rating of 6.6 out of 10 from a total of 873 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 27% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Trulance side effects in more detail. |
See also: Motegrity side effects in more detail. |
See also: Linzess side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Trulance prices |
View all Motegrity prices |
View all Linzess prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
N/A |
24 hours |
N/A |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 1 drugs are known to interact with Trulance:
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A total of 108 drugs are known to interact with Motegrity:
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A total of 59 drugs are known to interact with Linzess:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
January 19, 2017 |
December 14, 2018 |
August 30, 2012 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.