Rhofade Alternatives Compared
Rhofade | Doxycycline | Metronidazole topical |
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Rhofade (oxymetazoline) | Doxycycline | Metronidazole topical |
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Prescription only
Prescribed for Rosacea. Rhofade may also be used for purposes not listed in this medication guide. |
Prescription only
Doxycycline is an effective antibiotic that treats a wide range of infections. However, it is not usually recommended for children aged less than eight or pregnant women in the last half of their... View more |
Prescription only
Prescribed for Perioral Dermatitis, Rosacea, Bacterial Vaginosis, Balanoposthitis. metronidazole topical may also be used for purposes not listed in this medication guide. |
Related suggestions |
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More about Rhofade (oxymetazoline) | More about Doxycycline | More about Metronidazole topical | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Rhofade has an average rating of 3.2 out of 10 from a total of 135 ratings on Drugs.com. 23% of reviewers reported a positive effect, while 73% reported a negative effect. |
Doxycycline has an average rating of 6.4 out of 10 from a total of 1621 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 26% reported a negative effect. |
Metronidazole topical has an average rating of 6.6 out of 10 from a total of 331 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 25% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Rhofade side effects in more detail. |
See also: doxycycline side effects in more detail. |
See also: metronidazole topical side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Rhofade prices |
View all doxycycline prices |
View all metronidazole topical prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
N/A |
Acticlate, Adoxa, Adoxa CK, Adoxa Pak, Adoxa TT, Alodox, Avidoxy, Doryx, Doryx MPC, Doxy 100, Doxy 200, Doxy-Caps, Doxy-D, LymePak, Mondoxyne NL, Monodox, Morgidox, Okebo, Oracea, Oraxyl, Targadox, Uracil, Vibramycin View more | MetroCream, MetroGel, MetroGel-Vaginal, MetroLotion, Noritate, Nuvessa, Rosaclear, Rosadan, Vandazole View more | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
N/A |
23 hours |
N/A |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Summary unavailable. See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 48 drugs are known to interact with Rhofade:
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A total of 207 drugs are known to interact with doxycycline:
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A total of 8 drugs are known to interact with metronidazole topical:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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First Approval Date | ||||||||||||||||||||||||||
January 18, 2017 |
December 05, 1967 |
November 22, 1988 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.