Invokana Alternatives Compared
Invokana | Repatha | Simvastatin |
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Invokana (canagliflozin) | Repatha (evolocumab) | Simvastatin |
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Prescription only
Invokana is effective at lowering blood glucose levels in people with type 2 diabetes. It also reduces the risk of future cardiovascular events (such as a heart attack or stroke) and kidney disease... View more |
Prescription only
Repatha is a PCSK9 inhibitor that may be used to reduce LDL-C levels in people with primary hyperlipidemia and HoFH, and also to reduce the risk of cardiovascular events in adults with established... View more |
Prescription only
Simvastatin is effective at lowering cholesterol; however, it may cause muscle pain, particularly at higher dosages. Should not be used by people with active liver disease or in women planning a... View more |
Related suggestions Cardiovascular Risk Reduction
Popular comparisons
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More about Invokana (canagliflozin) | More about Repatha (evolocumab) | More about Simvastatin | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Invokana has an average rating of 5.8 out of 10 from a total of 257 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 35% reported a negative effect. |
Repatha has an average rating of 5.1 out of 10 from a total of 608 ratings on Drugs.com. 38% of reviewers reported a positive effect, while 49% reported a negative effect. |
Simvastatin has an average rating of 4.8 out of 10 from a total of 130 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 50% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Invokana side effects in more detail. |
See also: Repatha side effects in more detail. |
See also: simvastatin side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
N/A |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Invokana prices |
View all Repatha prices |
View all simvastatin prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
N/A |
N/A |
FloLipid, Zocor | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
13.1 hours |
408 hours |
N/A |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 371 drugs are known to interact with Invokana:
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A total of 2 drugs are known to interact with Repatha:
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A total of 311 drugs are known to interact with simvastatin:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||||||||||
No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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First Approval Date | ||||||||||||||||||||||||||
March 29, 2013 |
August 27, 2015 |
December 23, 1991 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.