Emsam Alternatives Compared
Emsam | Rexulti | Bupropion |
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Emsam (selegiline) | Rexulti (brexpiprazole) | Bupropion |
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Prescription only
Prescribed for Major Depressive Disorder, Depression. Emsam may also be used for purposes not listed in this medication guide. |
Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Related suggestions Depression
Major Depressive Disorder
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More about Emsam (selegiline) | More about Rexulti (brexpiprazole) | More about Bupropion | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Emsam has an average rating of 7.6 out of 10 from a total of 49 ratings on Drugs.com. 72% of reviewers reported a positive effect, while 14% reported a negative effect. |
Rexulti has an average rating of 6.5 out of 10 from a total of 459 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 27% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2850 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 20% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Emsam side effects in more detail. |
See also: Rexulti side effects in more detail. |
See also: bupropion side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Emsam prices |
View all Rexulti prices |
View all bupropion prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Other selegiline brands include: Atapryl, Eldepryl, Zelapar |
N/A |
Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
84 hours |
91 hours |
30 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 512 drugs are known to interact with Emsam:
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A total of 583 drugs are known to interact with Rexulti:
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A total of 497 drugs are known to interact with bupropion:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
February 27, 2006 |
July 10, 2015 |
December 30, 1985 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.