Aleve Alternatives Compared
Aleve | Tramadol | Ibuprofen |
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Aleve (naproxen) | Tramadol | Ibuprofen |
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Prescription and OTC
Prescribed for Back Pain, Ankylosing Spondylitis, Bursitis, Aseptic Necrosis, Muscle Pain, Chronic Myofascial Pain, Costochondritis, Diffuse Idiopathic Skeletal Hyperostosis, Dysautonomia, Fever... View more |
Prescription only
Tramadol is a strong opioid pain relieving medication that may be used to treat moderate to severe general and nerve-related pain. Tramadol may be habit-forming and misuse can cause addiction... View more |
Prescription and OTC
Ibuprofen is effective for the short-term relief of minor aches and pains and also reduces inflammation. The risk of stomach-related side effects is about half that seen with aspirin although the... View more |
Related suggestions |
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More about Aleve (naproxen) | More about Tramadol | More about Ibuprofen | ||||||||||||||||
Ratings & Reviews | ||||||||||||||||||
Aleve has an average rating of 7.0 out of 10 from a total of 152 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 25% reported a negative effect. |
Tramadol has an average rating of 7.0 out of 10 from a total of 1842 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 24% reported a negative effect. |
Ibuprofen has an average rating of 7.3 out of 10 from a total of 232 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 19% reported a negative effect. |
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Drug Class | ||||||||||||||||||
Side Effects | ||||||||||||||||||
See also: Aleve side effects in more detail. |
See also: tramadol side effects in more detail. |
See also: ibuprofen side effects in more detail. |
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Generic Availability | ||||||||||||||||||
Lower cost generic approved |
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all tramadol prices |
View all ibuprofen prices |
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Dosage Form(s) Available | ||||||||||||||||||
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Brand Names | ||||||||||||||||||
Other naproxen brands include: Aflaxen, Aleve Back and Muscle Pain, All Day Pain Relief, All Day Relief, Anaprox-DS, Comfort Pac with Naproxen, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan, Naprosyn, Naproxen Sodium DS, Pamprin All Day Relief View more | ConZip, Qdolo, Tramadol Hydrochloride ER | A-G Profen, Actiprofen, Addaprin, Advil, Advil Children's, Advil Film-Coated, Advil Infant's Concentrated Drops, Advil Junior Strength, Advil Liqui-Gels, Advil Migraine, Caldolor, Cap-Profen, Children's ElixSure IB, Children's Motrin, Childrens Ibuprofen Berry, Genpril, Help I Have An Aching Body, IBU-200, Midol IB, Midol Maximum Strength Cramp Formula, Motrin, Motrin Childrens, Motrin IB, Motrin Infant Drops, Motrin Junior Strength, Motrin Migraine Pain, Motrin Pediatric, NeoProfen, Nuprin, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Proprinal View more | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
18 hours |
5.2 hours |
4 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
Prior To 30 Weeks Gestation
Category D
Positive evidence of risk
Starting At 30 Weeks Gestation See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||
A total of 427 drugs are known to interact with Aleve:
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A total of 663 drugs are known to interact with tramadol:
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A total of 394 drugs are known to interact with ibuprofen:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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Disease Interactions | ||||||||||||||||||
First Approval Date | ||||||||||||||||||
January 11, 1994 |
March 03, 1995 |
September 19, 1974 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
N/A |
N/A |
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More Information | ||||||||||||||||||
Patient resources | ||||||||||||||||||
Professional Resources | ||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.